Open Source Drug Discovery

Tuesday, August 3, 2010

C2D Second Phase(The Grand Begining)


After sucessfull completion of phase first of CONNECT To DECODE programme the project has moved to its second phase of work.
There are several projects available at this phase for registration to the students who are willing to work .Exciting Opportunity for Summer Students who would like to be part of a global community trying to collaborate trying to understand the Biology of TB.
The sub areas of the second phase are as under-
Among these new projects two of them has already started , Cloning , Expression and Purification of Proteins-http://c2d.osdd.net/home/cep & Cheminformatics and Chemical Data Mining-http://c2d.osdd.net/home/cheminformatics headed by various PIs of the project.
students are getting various types of training under their project PI at different stages of work.

Initial steps of the project CLONING (CEP) is under wet lab experiments at Sastra University.
Cloning in Action can be seen at this link-http://c2d.osdd.net/home/cep/movs

Apart from all this a huge number of enthusiastic students have started there allotted assignments which are regularly updated on the project websites.

Previous Connect to Decode Programmes
Students & researchers can have the look at the link for the first phase of C2D programme here-


Bravo!! Congratulations to CSIR scientists and all the students involved in C2D phase First.


अद्भुत कार्य:-A Reality
Hundreds of scientists from across the country put in joint efforts at a three-day 'Connect 2 Decode' (C2D) conference to complete the final re-annotation of the 4,000- odd genes that determine how the TB bug lives and infects humans.
This is the first time that a comprehensive mapping of the Mtb genome has been compiled, verified and made publicly available. C2D's findings may contain critical data to unlock previously undiscovered details of tuberculosis (TB)
  • We need to have a balanced view between health as a right and health as a business. It is because there has been imbalance in this view that diseases like TB, with high mortality but low profitability, are neglected by the current system of pharmaceutical research,” said Dr. Samir K. Brahmachari, scientist and Director-General of the Council of Scientific and Industrial Research (CSIR).
  • C2D demonstrates the power of people to connect through the internet, particular young people, and accomplish complex research tasks. It is also a distinct move from a hierarchical based model of doing science towards one of equal collaboration.", project director Zakir Thomas said.

  • OSDD is a completely new formula across the world. Here we are making all our progress available to public. Anyone can take advantage and develop a drug based on our research. The aim here is not patents but drug discovery for a neglected disease," said Rajesh Gokhle, a senior scientist associated with the project.
Under the C2D project, researchers and students pooled their time and skills using online tools to provide insights into 4,000 genes of the deadly pathogen.
The MTB map has been hosted on a web portal (www.osdd.net) custom-developed by Infosys and uses an emerging format (Web 3.0) that allows users to get better search results while searching for data for research .