Supercomputing -GARUDA boot camp OSDD

Dear Friends,

For the past few months we all have been devoting our time and energy to make the Cheminformatics program of OSDD a success under the leadership of Dr.VINOD SCARIA &
Dr. Jaleel who is your Principal Investigator.
Dr.jaleel and team is continuosly working with students & researchers of OSDD-CHEMO div to make the job an enjoyable task with the help of online interactions,video tutorials and much more.
It has been our concerted endeavor to provide super compute power for our scientific work. Towards this end OSDD have tied up with CDAC Garuda grid on which most of you have registered. In order to facilitate your effective usage of Garuda grid resources, OSDD, in collaboration with CDAC is planning a Garuda Boot Camp on 27, 28 and 29 December 2010
Dr. Jaleel the PI will be leading the program and others hosting the workshop at MCC Calicut with Special arrangements to receive all the participants and make there stay comfortable & enjoyable.Boot camp is not only for Garuda training but for giving some idea in data mining techniques , bio informatics and computational chemistry .
Dr. Jaleel and his team will be ready to receive All participants including students,Researchers & scientists working with OSDD few days in advance at Bangalore city base.
Project Director Zakir Thomas has described the God own`s country with some interesting facts
""""""""Calicut is a small but historic city. Thomas Friedman, in his book the ‘World is Flat’ refers to the travel of Vasco de Gama round the cape of Good Hope, to India, where he landed near Calicut. He says Gama went back with tons of merchandise and reported to the King that the world is round. I hope that in today’s interconnected world, this voyage of yours to this historic city will let you experience how the web has made this a flat world, at least so far as access to knowledge is concerned.""""" Zakir thomas has given there best wishes to all participants joining at Malabar Christian college-calicut """"""""
Participants are also very eager to meet all members and researchers of OSDD chemoinformatics group at the bootcamp and share vision and idea regarding Open Source Drug Discovery.
As the crew team of OSDD karnatka leading by Dr Prasad M Alex ,Associate Professor in Chemistry is going to take care of all the members at BANGALORE base who all are joining at bootcamp.
Crew team will be at Bangalore from 22 nd morning to 23 eve at both railway station (Bangalore city and yaswanth pura ) for assisting you all .. it is advisable to all participants to get there tkts reserved to reach Bangalore on 22nd DEC 8.00am to 23 rd evening December.

Thanks to you all once again ,Hope we will achieve one step closer to our goal after getting the SUPERCOMPUTING knowledge from all of the OSDD & MCC calicut scientists .

C2D Second Phase(The Grand Begining)

After sucessfull completion of phase first of CONNECT To DECODE programme the project has moved to its second phase of work.
There are several projects available at this phase for registration to the students who are willing to work .Exciting Opportunity for Summer Students who would like to be part of a global community trying to collaborate trying to understand the Biology of TB.
The sub areas of the second phase are as under-

• Cloning , Expression and Purification of Proteins-http://c2d.osdd.net/home/cep
• Chemistry and Chemical Synthesis of Small Molecules
• Cheminformatics and Chemical Data Mining-http://c2d.osdd.net/home/cheminformatics
• Volunteer Compute Grid and Software for the Grid

Among these new projects two of them has already started , Cloning , Expression and Purification of Proteins-http://c2d.osdd.net/home/cep & Cheminformatics and Chemical Data Mining-http://c2d.osdd.net/home/cheminformatics headed by various PIs of the project.
students are getting various types of training under their project PI at different stages of work.

Initial steps of the project CLONING (CEP) is under wet lab experiments at Sastra University.
Cloning in Action can be seen at this link-http://c2d.osdd.net/home/cep/movs

Apart from all this a huge number of enthusiastic students have started there allotted assignments which are regularly updated on the project websites.

Previous Connect to Decode Programmes
Students & researchers can have the look at the link for the first phase of C2D programme here-

Summer of 2010 -https://sites.google.com/a/osdd.net/c2d-01/
C2D10 Meeting -http://c2d10.osdd.net/

Bravo!! Congratulations to CSIR scientists and all the students involved in C2D phase First.

अद्भुत कार्य:-A Reality
Hundreds of scientists from across the country put in joint efforts at a three-day 'Connect 2 Decode' (C2D) conference to complete the final re-annotation of the 4,000- odd genes that determine how the TB bug lives and infects humans.
This is the first time that a comprehensive mapping of the Mtb genome has been compiled, verified and made publicly available. C2D's findings may contain critical data to unlock previously undiscovered details of tuberculosis (TB)

• We need to have a balanced view between health as a right and health as a business. It is because there has been imbalance in this view that diseases like TB, with high mortality but low profitability, are neglected by the current system of pharmaceutical research,” said Dr. Samir K. Brahmachari, scientist and Director-General of the Council of Scientific and Industrial Research (CSIR).

• C2D demonstrates the power of people to connect through the internet, particular young people, and accomplish complex research tasks. It is also a distinct move from a hierarchical based model of doing science towards one of equal collaboration.", project director Zakir Thomas said.

• OSDD is a completely new formula across the world. Here we are making all our progress available to public. Anyone can take advantage and develop a drug based on our research. The aim here is not patents but drug discovery for a neglected disease," said Rajesh Gokhle, a senior scientist associated with the project.

• "This marks the beginning of the efforts of C2D to align R&D with public health and to use the full potential of the open source model for the development of medical technologies and drug discovery for neglected diseases," Samir Brahmachari, Director General, CSIR said.
• CSIR news letter for the month of May which include Connect to Decode Conference news on page 5. http://www.niscair.res.in/sciencecommunication/RnDNewsLetters/csirnews2k10/csirnews_may10.pdf
  
  

Under the C2D project, researchers and students pooled their time and skills using online tools to provide insights into 4,000 genes of the deadly pathogen.
The MTB map has been hosted on a web portal (www.osdd.net) custom-developed by Infosys and uses an emerging format (Web 3.0) that allows users to get better search results while searching for data for research .

Historical workshop in the World

Historical workshop in the World...----
As the last day of the OSDD conference came to the end after IPW team generated the Mtb network of project MAPATHON There was a lot of enthusiasm and excitement. Prabhakar tried his best to pin up the poster with help from the team, and Samik and Yukiko providing full support to them. The Project Director, Zakir Thomas, was also a part of this activity .
At the moment of valedictory session N. R. Narayana Murthy the Founder-Chairman of Infosys Technologies Limited has unveil gene map for TB on portal os CSIR,
As this was the Historical workshop in the World which was continuously supported by India 800 foundation lead by Lord Bhatia has surprised the members of OSDD c2d 2010 Mtb project by presenting them the E-machines LAPTOPS to every selected member of c2d2010 as the royality of there dedicated work and had requested to every one to have a word from the Novel Book Gitanjali .It is a book to feel and cherish that is wrote by the great writer Rabindra Nath Tagaore.


TO BE CONTINUED...............................

The Second day of C2D meet of OSDD -10th April 2010

10th April 2010,The Second day of the international conference of OSDD C2D20120.....has started at JNU CAMPUS,New Delhi
THe session started by GPS Raghava(IMTECH)- MANAGING AND ANNOTATING M.Tb DATA USING DrugPedia AND MycoTB--- ON THE SILICO approach towrads the war against Mtb using OSDD PLATFORM as the C2D was an EXPERIMENT TO INVOLVE STUDENTS, .......and it has rocked....................
Later the session proceeds with the SET UP OF MAPATHON(creation of network) with konnichiwa(-hello in Japanese) to all from Matsuoko Yukiko-SBI ,Here all the members from OSDD learnt about the Pathway Modeling and Cu ration using CellDesigner + Payao and then all were moved directly to a a kind of power session to complete the task of creating the network ............................
and the members were really expressed there arigatou-(thanks) to Matsuoko Yukiko-SBI, Samik Ghosh sir & Hiroaki Kitano-SBI,And the they expressed there arigatou to the IGIG members who helped all the kid scientist in perfroming there task.
The group work session was too much hectic to handle but interesting to work on too........
At the end of the day The TBGO TEAM interacted with each other in presence of Dr.Sameer Brahmchari sir,Zakir Thomas Sir & Dr.Vinod sir,and discussed there experiences on the C2D project and with lots of enjoyment ,,,,,,,,,,,,nd then at last all were forcefully directed by SUKHBIR Sir to Dinner....................and it was true that now TBGO group were facing the prob in finding food due to time delayed by TBGO group interaction................bt at last all was set and back to Hostels by busses..........................................

10th April the second day Started at JNU

The young minds are ready for science journey to build a strong INDIA through "C2D"
Hence for the second day of the conference the rocking team already moved to JNU for the Set up of MTb mapathon project phase under the guidance of Samik Ghosh & Matsuoka Yukiko(SBI)...........

At the end of the First day-9th april2010

After a lot of enjoyment & excitement with a sequence of eminent speakers from all over the world at TEEN MURTI BHAVAN (OSDD for e.g..Ms.karin Timmermans-WHO,HIROAKI KITANO(sbi),Lord Amir Bhatia and many more .............
and the day came to the end at late night after a panel disscussion between Team members with the mentors......
All the members of C2D have enjoyed the sparkling moments.
at last all were tired but still much of the enthusiasm is left so nobody has moved to there rooms as it is shown in the pic..................
Last but unended session of the day moved with lot of enjoyment With sukhbir sir AT VISHWA YUWAK KENDRA(INTERNATIONAL YOUTH HOSTEL)...........................

GO Gone crazy On the stage( TBGO )

Motivated Students at the historic moment of science

And at last the precious Sparkling moment arrive

At last the wait is over for the precious moment of jamboree meet at Delhi !!!
The most awaited day has dawned
The dedicated kid scientists arrived VYK with face full of smiles and excitement.. They met their team members with whom they were working virtually froma long time on this mamoth project. They were much more excited by the surprise gifts provided by the OSDD ..

In this Pleasant morning, the OSDD c2d programme started off with a warm welcome by ZT after the registration process and the students are awaiting the most awaited moment, the Speech of the Minister of Science and Technology Dr.Prithviraj Chavan. SKB introduced the chief guest to the gathering.

THE WAIT IS OVER

The Last Mile
IPW Team is pushing hard to finish the last mile of data QC before coming to the on-site phase at Teen Murti. The Team at this hour (11:14 pm) is sitting in the lounge of the Guest house concentrating on the task. They have shown unending commitment to finish this humongous task in such a small period of time!!!

Cheers to all the members who have made C2d possible!!!!

Many of the participants of Connect to Decode must be boarding trains today and tomorrow. Do take enough rest while in train. When you are at the onsite phase your PIs have plenty of assignments for you that might keep you awake almost the whole night during your stay. The IPW and TBGO team are working without a break to meet the schedule. This is probably the most intensive QC exercise you can come across. So its work time folks. But you bet, you are going to have a ball of a time. It will be one great learning exercise – for everyone- including the Connect to Decoders, the PIs, the organisers and the rest of us. All of us are eagerly awaiting your arrival. Buckle up for the fast drive!
---ZAKIR THOMAS

"TBGO" ON GO

The TB GO team has moved to onsite mode. A nerve centre has started functioning at the CSIR IGIB facility at Naraina. Yes, the same centre which sequenced human genome and the one which hosts the IT infrastructure of OSDD. Amidst the hum of the machines and scientists in their coats, a bunch of Connect to Decoders has moved in today to Dr. Vinod Scaria’s lab.

It is indeed an interesting lab. One which any bio-informatician would like to be part of. A series of servers lined up in a state of the art server room gives out a regular hum and lights go on and on. Few rooms away are state of the art sequencing machines. Adjacent to the server room separated by a glass, is a row of computers.

As you walk in a bunch of Connect to Decoders are already infront of the screens and immersed in working. They had just reached New Delhi railway station two hours ago. This is what is called hitting the ground running.

In the afternoon they had an unusual visitor. Jean Marie from UK who is writing a book on innovation in China, India, South Africa and Brazil was wanting to know about OSDD. What better way to know about OSDD but to speak to Connect to Decoders.

The GO team is here to do the last bit of QC. Or, may be, they will throw a surprise when you meet them. You don’t get a bunch of bright young minds and expect nothing, right?
-- by Zakir Thomas

BEST 13 OF IPW AT ONSITE PHASE OSDD

 

First Network

First Network
It is exciting and emotional to see the First Network that the IPW Team generated using Cell Designer for the first set of quality checked data !!! Samik from the Systems Biology Institute. Japan, has been interacting with the Team working from Delhi through Skype calls. Today we also interacted with The Chief Mentor and Project Director of OSDD through Skype and had interesting discussions on network analysis. Watch out for more...we are at it.
Posted by Anshu

Glimpse of onsite IPW team at C2D2010

 

Away from the buzz of Delhi, nestled among green trees frequented by birds, is CSIR's Human Resources Development Centre at Ghaziabad. HRDC is having a bunch of unusual group. Usually frequented by scientists and leaders of CSIR, is now the hub of Connect to Decode activity. Dr. Anshu Bhardwaj has quietly started the onsite phase of Pathway Annotation project. Her handpicked team leaders are quietly doing the Quality Control (QC) check of the data annotated by the team.

C2D Programme Update

We have just updated the Programme for C2D10. We have added a few more speakers and workshops that we feel the C2D team would enjoy.

The Programme details are also available at the C2D10 Website at URL: http://c2d10.osdd.net/programme
by Dr. Vinod Scaria

Zakir Thomas"Audacity of Hope"

Friday, March 26, 2010
Audacity of Hope
Connect to Decode onsite phase is just two weeks away! I cant wait to meet the heroes who have been so far contributing online. The work done so far is impressive. But to me more impressive is the process of collaboration and the lessons learned in organising such hugely collaborative programme. You have demonstrated that OSDD can handle huge volumes of data.
More than that, you have announced before hand that the results will be made available in the open to the world on 11 April 2010. How many science projects do this? Of course, Space programme does it. The rocket has to blast off on the designated day at the appointed time. But how many science projects?
When we were discussing Connect to Decode, Dr. Sukanya Dutta asked: why are you all stretching yourself? 'Nobody works to a deadline in Science!' Well my reply to her was if we are to do what everyone does, then why OSDD? Yes, that is what sets OSDD apart. We do things differently. We do not tread the beaten path. It is a new way indeed.
Yes, your hard work demonstrates that OSDD is a new way of doing science!
Announce that the result of a project will be available on a date, even as the project is ongoing? Isn’t this the audacity of hope?!

With Regards
Zakir Thomas
Project Director, Open Source Drug Discovery (OSDD) &
Head DG's Technical Cell,
Council of Scientific and Industrial Research

Researchers Find Way to Kill Drug-Resistant TB Drug Discovery & Development - March 22, 2010

Researchers at Albert Einstein College of Medicine of Yeshiva University have found two novel ways of killing the bacteria that cause tuberculosis (TB), a disease responsible for an estimated two million deaths each year. The findings, published in the March 21 online issue of Nature Chemical Biology, could lead to a potent TB therapy that would also prevent resistant TB strains from developing.

read the complete article here
http://www.dddmag.com/news-Researchers-Find-Way-to-Kill-Drug-Resistant-TB-32210.aspx

CUSAT joins OSDD as a Partner Institution

The Inter-University Centre for Intellectual Property Rights of CUSAT joins OSDD as a Partner Institution


One of the renowned Intellectual Property Law Schools of India, The Inter-University Centre for Intellectual Property Rights of Cochin University of Science and Technology (CUSAT) has joined OSDD as a partner institution. This Inter University Centre will provide OSDD advice on Intellectual Property and on other legal matters.

President of India on OSDD

DECADE OF INNOVATION

LOK SABHA

President of India in her address to Parliament on 4th June 2009 mentioned that next ten years would be dedicated as a Decade of Innovation. Prime Minister of India in the 97th Session of Indian Science Congress held on 3rd January, 2010 at Thiruvananthapuram, Kerala also mentioned in his speech that the Government has declared 2010-2020 as the “Decade of Innovations”. The main aim of this declaration is to develop an innovation eco-system in the country to stimulate innovations and to produce solutions for the societal needs in terms of healthcare, energy, urban infrastructure, water and transportation.

The Ministry of Science and Technology is promoting innovations through various schemes such as Technopreneur Promotion Programme (TePP); technology business incubators under Science and Technology entrepreneurship Development scheme; Drugs and Pharmaceuticals Research; Innovation Clusters; Small Business Innovative Research Imitative (SBIRI); Biotechnology Industrial partnership Programme (BIPP); open source drug discovery (OSDD) projects and grass root innovations through National Innovation Foundation. Finance Minister in his budget speech on 26th February 2010 has announced increase of weighted deduction for expenditure incurred on scientific research and development from 150 per cent to 200 per cent by companies in an approved in-house research and development facility and weighted deduction for contribution to approved entities for the purpose of scientific research from 125 per cent to 175 per cent.

This was stated by Shri Prithviraj Chavan, the Minister of State (I/C) for Science and Technology and Earth Sciences in the Lok Sabha today.

OSDD in Biospectrum-Asia Edition

More than 2000 researchers join OSDD to tackle TB bacteria

Bangalore, Nov 27, 2009: A unique Indian attempt to pool the expertise of researchers in the country and abroad through a collaborative, sharing model of exchanging key discoveries to find a cure to the dreaded tuberculosis(TB) disease has got a boost with more than 2000 researcher joining the effort within a short span of 14 months of its launch. November 23, 2009 is another red letter day in the annals of the programme, called the Open Source Drug Discovery (OSDD), launched in September 2008, when the 2000th member joined this network. In fact, on this day the total number of people on this collaborative effort stood at 2011. The initiative is mentored by the director-general of India’s publicly funded research agency, Council of Scientific and Industrial Research (CSIR), Dr Samir K Brahmachari, himself a top geneticist. OSDD is a $ 38 million ( Rs 175 crore) collaborative effort, launched in September 2008, to expand our understanding of the biology of the dreaded Mycobacterium tuberculosis (Mtb) which could lead to the development of novel drugs to treat the disease and if possible prevent its occurrence. It is one of the oldest and most neglected diseases which kills millions of poor people around the world. . It is a concept to collaboratively aggregate the biological and genetic information available to scientists in order to use it to hasten the discovery of drugs. This will provide a unique opportunity for scientists, doctors, technocrats, students and others with diverse expertise to work for a common cause. “ Though Mtb was sequenced a decade back, the standard databases have not been annotated in real biological processes, more than 1000 of the near 4000 genes encoded by the organism. This is symptomatic of the problem of neglected diseases of the poor,” said Dr Zakir Thomas, the OSDD project director at CSIR coordinating the mammoth task. The massive work done by the programme and the increasing interest level in the project has won all round praise so far. “To have 2000 registered users within a year is a fantastic achievement. I am really proud of the efforts,” said a congratulatory message from the former chief of CSIR, Dr R A Mashelkar. Hundreds of such congratulatory messages have been exchanged in the network in the last few days. Interestingly even some of the skeptics of such collaborative efforts, in contrast to the highly secretive, proprietary nature of drug discovery programs, have appreciated the OSDD’s efforts. “ I was a skeptic about OSDD when we discussed it about a year ago. I am always happy to be proven wrong, however, especially where the results of the other way of doing things are positive, “ wrote Dr Richard Wilder, a senior executive of Microsoft. In fact, there is a widespread global interest about the OSDD project. It is designed along the lines two major collaborative projects which are successful global models: the international consortium approach that decoded the human genome in the 1990s and the open source software development that led to the creation of the free-sharing Linux operating system. Computer giant HP is a key supporter of the program. Other computer software companies too are keenly watching the project’s progress. “ This ( 2000 members) is great news! An important milestone. Congratulations to everyone and I am hoping for an exponential growth. A number of 20K by Dec-2010 would be a good number to aspire for…,” says a post by Mr Uday Bhaskarwar, a vice president at Bangalore-based Infosys Technologies. The program has taken up nearly 120 projects which are online now for every one work. Some of these projects have produced excellent results. The community has several credits to be proud of including open peer review, open funding review, large number of real time data on open lab notebooks. “All our funded projects have posted their quarterly progress online, including their ongoing research results. The first OSDD international publication (PMID: 19683474) arising out of virtual collaboration, with due author credits even to collaborating students, is available online, “said Dr Thomas. Of course, the 2000-member celebrations are already over. The project team is moving towards its next goal with renewed vigor. The next big leap planned is to completely re-annotate the MTb genome for which OSDD has launched ‘Connect to Decode’ 2010 (c2d.osdd.net). Within hours of its announcement, more than 500 researchers have volunteered to join this new initiative. The OSDD project team hopes to select 150 members from this group and bring them together face-to-face in New Delhi in April 2010 and complete the task methodically. BioSpectrum Bureau

IPW-on-site Annotation phase

IPW team embarks on the on-site Annotation phase The IPW team will get together tomorrow in Delhi to embark on the on-site annotation of the TB pathways. The team mentored by Dr Anshu Bhardwaj will assemble for a couple of weeks to top up the annotations and perform the QC.

OSDD on youtube

OSDD on youtube http://www.youtube.com/watch?v=qVMONhi_wk8

Here the video speaks all about the OPEN SOURCE DRUG DISCOVERY,(osdd)and how its work
A keynote by-Samir K Brahmachari DG, CSIR(seceratery DSIR)

Invitation to Join the OSDD TBGO Annotations QC and Wrapup

Invitation to Join the OSDD TBGO Annotations QC and Wrapup
Dear OSDD Enthusiasts

As part of the connect to Decode Initiative, early this year we had organised a programme for collaborative annotation of the Mycobacterium tuberculosis genome. With active community help, we were able to annotate most of the genes in the organisms with standard Gene Ontology (GO) terminologies. We are planning to do the final QC and wrapup the first round of annotations which we hope to start releasing to the world on 9-11 April 2010 with the C2D10 http://c2d10.osdd.net meeting.

This is an open call to student volunteers, researchers and scientists to contribute to this initiative by verifying the annotations using literature and other evidence. A best selected team of few volunteers would also be invited to attend the C2D10 http://c2d10.osdd.net an event at Delhi, in addition to winning exciting prizes. This is also open to all contributors of TBGO who have not been able to keep the pace of the activities and have dropped off at different levels.

All interested participants may join any of the team leaders listed below DIRECTLY. The team leaders would guide you on how to go about the annotations.

Dipon-diponlove@hotmail.com
Gourja -gourja@gmail.com
Deepa-deeps8891@yahoo.co.in
Vivek-vbhardwaj247@gmail.com
Chris-chrissheba@gmail.com
Sangeetha-sangeethabalaguru@gmail.com

Please feel free to circulate it among your friends and colleagues or volunteers who might be interested in participating.

The LAST DATE FOR APPLICATIONS IS 25th MARCH 2010

Best regards
Vinod

Open source: the way forward in the search for new treatments for the infectious diseases of poverty

TropIKA.net Examines How Researchers Are Using 'Open-Source Principles' To Bolster TB Drug Development
TropIKA.net examines the efforts of a collaboration known as the Open Source Drug Discovery Foundation (OSDD), which is using "open-source principles" in hopes of accelerating the development of affordable drugs for diseases such as tuberculosis,malaria and leishmaniasis. "OSDD, the brainchild of India's Council of Scientific and Industrial Research (CSIR) in Delhi, is dedicated to developing drugs more cheaply by copying the model of the immensely successful open-source software movement," TropIKA.net writes. "OSDD collaborators are working on around 180 projects aimed at combating TB," according to the news service (Anderson, 3/17).

C2D10- conference schedule

Connect to Decode' Jamboree from April 9th -11th 2010 at #Delhi

Kudos to C2D TBGO volunteers for completing the gene annotation: http;//c2d.osdd.net
Connect to Decode Annotation Projects Nearing Completion. TB Glycomics Project already Successfully Completed and others the pathway annotations & gene ontology are near to completion.
Annotators who have been working exhaustively on a collaborative platform on re-annotating the Mtb genome, are invited to the final round of Quality Control and data integration.

What is Connect to Decode ?

What is Connect to Decode ?
Open Source Drug Discovery (OSDD) Project in its quest towards conquest of Tuberculosis, is launching a massive initiative to further the understanding of the biology of the causative organism, Mycobacterium tuberculosis. The objective is to accelerate the discovery of novel drugs for TB, a disease neglected by Pharmaceutical enterprises

About Connect to Decode 2010
The "Open Source Drug Discovery" http://www.osdd.net/ project envisages the sourcing of geographically separated scientific manpower and resources towards collectively solving the problem of drug discovery against Mycobacterium tuberculosis, and is mentored directly by Prof. Samir Brahmachari, the Director General of CSIR.
The project is presently building an infrastructure of federated resources consisting of analytical instruments, computational resources and personnel distributed across the country. It seeks to bridge the unequal distribution of resources required for science and education by connecting resource-rich CSIR laboratories and central universities with participants students and research personnel from smaller less equipped institutions. OSDD seeks to fund 30 research facilities in universities/colleges and interface them to experts with existing laboratories. This massive initiative is to further the understanding of the biology of the causative organism of Tuberculosis, tuberculosis, Mycobacteriumfocussed on identifying a cure. The community of users for the OSDD project is now over 2000 persons.
"CONNECT to DECODE" (C2D) http://c2d.osdd.net/ is an open, collaborative, large scale effort to comprehensively annotate the whole genome of Mycobacterium tuberculosis. This research program aims to understand this pathogenic bacteria by involving young and bright minds from all across the globe, are working on projects to annotate the tuberculosis genome scheduled to complete at the end of March, 2010. These participants are distributed over colleges across the country.
The projects have been centered around the following themes :-
-> Pathway/Interactome Annotation
-> Gene Ontology Annotation
-> Protein structure/Fold Annotation
-> Glycomics of Mtb
-> Immunome of Mtb